Precision oncology for RET-related tumors
Aberrant activation Baby Shower of the RET proto-oncogene is implicated in a plethora of cancers.RET gain-of-function point mutations are driver events in multiple endocrine neoplasia 2 (MEN2) syndrome and in sporadic medullary thyroid cancer, while RET rearrangements are driver events in several non-medullary thyroid cancers.Drugs able to inhibit